2021 Abstracts from the Burkitt Lymphoma Genome Sequencing Project
In June 2021, two Abstracts were accepted and presented at the 16th International Conference on Malignant Lymphoma virtual meeting.
The first abstract titled Key genetic and molecular aberrations identified in both adult and EBV-positive Burkitt lymphoma patients, was presented by Nicole Thomas, PhD candidate in the Department of Molecular Biology and Biochemistry, Simon Fraser University, BC, Canada. The reference for this abstract is: Hematological Oncology, Volume 39, Issue S2, Supplement: 16th International Conference on Malignant Lymphoma, Virtual Edition, 18-22 June, 2021, pp. 114-116. The data that were presented highlight key mechanisms underlying BL pathogenesis and key genetic differences based on age and EBV status.
The second abstract titled Copy number variation analysis identifies distinct genomic features in adult Burkitt lymphoma was presented by Kostiantyn Dreval PhD, a Post-Doctoral Fellow in the Department of Molecular Biology and Biochemistry, Simon Fraser University, BC, Canada. The reference for this abstract is: Hematological Oncology, Volume 39, Issue S2, Supplement: 16th International Conference on Malignant Lymphoma, Virtual Edition, 18-22 June, 2021, pp. 113-114. The key findings that were presented demonstrate that adult BL has a distinct CNV profile compared to pediatric BL, suggesting either distinct mutational processes or selective pressures in this malignancy. The differences are not explained when samples are stratified based on EBV status or sex.